Endoplasmic reticulum Assignment Help
Endoplasmic reticulum is an organelle present in eukaryotic cells. It is a network of tubules, vesicles and cisternae that helps in modeling and export of proteins in other organelles.
Endoplasmic reticulum can be divided into two types: rough ER and smooth ER. On one hand rough Endoplasmic reticulum synthesis protein whereas on the other hand smooth endoplasmic reticulum synthesis lipid. Beside this two, Sarcoplasmic Reticulum is also there that regulates calcium level.
Endoplasmic reticulum is a double membrane bound organelle with network of cisternae. These cisternae are held together by cytoskeleton. The main function of ER is the synthesis and export of protein and lipid to different other organelle and compartments.
Rough Endoplasmic reticulum: as said earlier, it is specialized for the synthesis and export of protein. It is designated as rough because the outer layer of this ER has ribosome attached to it. Therefore, first the protein is manufactured by the ribosomes and ER thus blends those proteins and hence prepares them for exporting it to the respective compartments.
Some of the main functions of Rough Endoplasmic reticulum(RER) are:
- Manufacture of lysosomal enzymes with mannose-6- phosphate as a marker.
- Manufacture of secretory proteins.
- Integral membrane proteins are synthesized in RER.
- N- linked glycosylation takes place in RER.
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Smooth ER: this endoplasmic reticulum synthesis lipid, steroids and phospholipids. This SER is present in testis, ovaries and skin oil gland in high amounts. Glucose-6 phosphate is the enzyme present in SER and hence this helps in lipid synthesis and export.
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